Serum requirement for apoferritin induction in rat liver slices.
نویسندگان
چکیده
s 138 Correspondence: Sea-Blue Histiocytes 148
منابع مشابه
Serum Requirement for Apoferritin Induction
In studies of ferritin induction, liver slices failed to respond favorably to iron added directly to the suspending medium unless serum was added. The addition of 5 , g Fe/mi to slices in who!e serum accelerated the incorporation of radioleucine into ferritin 2.5fold. The favorable effect of serum on iron-induced ferritin synthesis was correlated with its attenuation of the toxic effects of the...
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Increased synthesis of rat liver apoferritin in response to iron administration was studied in rats that had lost RNA from the liver through protein deprivation. At two levels of iron dosage there was no loss of capacity to respond to the iron. Since the action of iron is known to occur through a cytoplasmic mechanism, these findings suggest that the messenger RNA for ferritin is stable during ...
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عنوان ژورنال:
- Blood
دوره 39 2 شماره
صفحات -
تاریخ انتشار 1972